FMOC-PHE(F 5)-(C*CH2)OH

FMOC-PHE(F 5)-(C*CH2)OH - Names and Identifiers

Name	Fmoc-(S)-3-Amino-4-(pentafluoro-phenyl)-butyric acid
Synonyms	RARECHEM AK PT F045 FMOC-BETA-HOPHE(F)5-OH FMOC-PHE(F 5)-(C*CH2)OH FMOC-PENTAFLUORO-L-BETA-HOMOPHENYLALANINE FMOC-(S)-3-AMINO-4-PENTAFLUOROPHENYLBUTANOIC ACID Fmoc-(S)-3-Amino-4-(pentafluoro-phenyl)-butyric acid FMOC-(S)-3-AMINO-4-(PENTAFLUORO-PHENYL)-BUTYRIC ACID N-BETA-(9-FLUORENYLMETHOXYCARBONYL)-L-HOMO(PENTAFLUOROPHENYL)ALANINE N-(9-FLUORENYLMETHOXYCARBONYL)-(S)-3-AMINO-4-(PENTAFLUOROPHENYL)BUTANOIC ACID
CAS	270063-43-9

FMOC-PHE(F 5)-(C*CH2)OH - Physico-chemical Properties

Molecular Formula	C25H18F5NO4
Molar Mass	491.41
Storage Condition	2-8°C

FMOC-PHE(F 5)-(C*CH2)OH - Risk and Safety

Hazard Class

IRRITANT

FMOC-PHE(F 5)-(C*CH2)OH - Introduction

Fmoc-(S)-3-Amino-4-(pentafluoro-phenyl)-butyric acid is an organic compound with the following properties:

1. Appearance: white crystalline solid
2. Molecular formula: C17H14F5NO2
3. Molecular weight: 353.29g/mol
4. Melting Point: 135-140 ℃
5. Solubility: in some organic solvents (such as dimethyl sulfoxide, hydrofluoric acid) can be dissolved

The main use of Fmoc-(S)-3-Amino-4-(pentafluoro-phenyl)-butyric acid is in the synthesis of peptides and proteins. It is usually used as a protecting group in solid phase synthesis, with the function of protecting the amine group. The compound has high efficiency and selectivity in solid phase synthesis and peptide synthesis reaction.

The method for preparing Fmoc-(S)-3-Amino-4-(pentafluoro-phenyl)-butyric acid includes the following steps: amino and pentafluorophenyl groups are first introduced onto butyric acid by a synthetic reaction and the product is generated under appropriate conditions. Then, an Fmoc protecting group is introduced to the amino group, and the amino group is protected. The introduction of the protecting group can be carried out using the corresponding reactants and solvents.

When using Fmoc-(S)-3-Amino-4-(pentafluoro-phenyl)-butyric acid, you need to pay attention to the following security information:
1. The compound is irritating and should avoid skin and eye contact.
2. Wear appropriate protective equipment during operation, including lab gloves and goggles.
3. During storage and handling, care should be taken to prevent contact with oxidants and strong acids/bases to avoid dangerous reactions.
4. Use the process to maintain a well-ventilated laboratory conditions. In case of carelessness, spills and waste should be properly disposed.

Last Update：2024-04-10 22:29:15